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Structural studies of the YedU stress protein
The knowledge of stress proteins is important for understanding stress response, pathology of a broad set of diseases, and the development of therapeutics. The Escherichia coli YedU stress protein, also known as Hsp31, ...
Microvascular endothelial response to cocaethylene exposure: morphological and molecular observations
Cocaethylene (CE) is an active metabolite of cocaine and ethanol and is a toxicant of physiological relevance due to the high rate of cocaine and ethanol co-exposure (~80%) in cocaine abusers. It has prolonged action and ...
Respect for research subjects: Reality or rhetoric?
The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research (National Commission) identified respect for persons as one of three fundamental ethical principles for research in its ...