Bax translocation to the mitochondria has been well-characterized to induce apoptotic cell death in multiple injury paradigms. However, pro-cell death actions for Bax outside of the mitochondria remain understudied. Bax’s ...

One of the critical steps involved in cellular oxidative stress is the peroxidation of membrane lipids. The downstream effects of the autocatalytic lipid peroxidation (LPO) cycle are widespread and involve several processes. ...

Both stroke and cancer are major public health problems that inflict immeasurable suffering to victims and their families. The treatment options currently in place for both stroke victims and cancer patients are limited. ...

Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) has a tripartite negative-strand genome, causes a mosquito-borne disease that is endemic in sub-Saharan African countries and results in large epidemics ...