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Effector CD4+ T lymphocyte resolution of acute HSV infection at genital and neuronal sites, and the manipulation of CD4+ T cell responses via TLR ligand-induced proinflammatory cytokine milieus
In primary infection, CD8+ T cells are important for clearance of infectious HSV from sensory ganglia. We present evidence of CD4+ T-cell-mediated clearance of infectious HSV-1 from neural tissues. In immunocompetent ...