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Zinc ion homeostasis in cellular physiology and experimental models of traumatic brain injury
A major yet unsolved quest in treating traumatic brain injury (TBI) is the understanding of the secondary cellular injury that contributes to cell death. Whether zinc ions are toxic or protective in TBI is controversial. ...
Replication-associated base excision repair Of oxidized bases in the mammalian genome
Reactive oxygen species (ROS), the most pervasive endogenous and radiation-induced genotoxic agents induce strand breaks and a plethora of base lesions in DNA that (except double-strand breaks) are repaired via the DNA ...