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Genetic determinants of NEIL2 transcription
The human genome is constantly damaged by reactive oxygen species (ROS) which produce a multitude of oxidative DNA lesions that can lead to mutations, genomic instability, and ultimately, to the development of cancer and ...
Reactive oxygen species involvement in gabaergic dysfunction in neuropathic pain
Neuropathic pain caused by peripheral nerve damage results in ectopic neuronal excitability, primary sensory neuron degeneration, loss of inhibition by spinal GABAergic neurons and more importantly, the development of ...
The role of reactive oxygen species as mediators of respiratory syncytial virus induced pulmonary inflammation
Respiratory Syncytial Virus (RSV) is the leading cause of epidemic respiratory tract illness in children worldwide. Although the mechanisms of RSV-induced airway disease are unknown, experimental evidence suggests that ...