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Characterization of Candidate Mutations for Use in a Live Attenuated West Nile Virus Vaccine
West Nile virus (WNV) is a mosquito-borne flavivirus that causes neurological disease and fatalities annually in the United States and Europe, but no human WNV vaccines have been licensed. Studies of WNV vaccine candidates ...
Characterization of single-cycle flavivirus particles for use as a vaccine to prevent West Nile disease and to examine immune responses to flavivirus infection
(2009-08-28)
West Nile virus (WNV) is responsible for the largest outbreak of viral encephalitis in the history of North America, yet there are no vaccines available to prevent this disease. To address these needs we have developed ...