Browsing Published ETD Collection by Title
Now showing items 138-157 of 741
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Defining Molecular Mechanism of Egress in Cryptosporidium
Recent studies have identified Cryptosporidium as a major contributor to childhood disease in endemic areas. Current interventions are not ideal where only few have demonstrated anti-cryptosporidial activity and are often ... -
Defining the Normal Range of Cerebrospinal Fluid Opening Pressure in Adults: A Systematic Review
It has been theorized that the visual changes observed in the astronaut population described by the Spaceflight Associated Neuro-ocular Syndrome (SANS) are related to elevated intracranial pressure (ICP). To better understand ... -
Degradational and Transcriptional Investigations of the RAF Kinase Inhibitory Protein
RKIP (Raf-1 kinase inhibitory protein) is a novel potent metastasis suppressor by its function of inhibiting ERK pathway, NF-κB pathway, and GRK-2. RKIP expression level is reported to be critical in the differentiation ... -
DELINEATING REGULATORY PATHWAYS OF NOVEL CANCER STEM CELL MARKER, DCLK1-S, FOR TARGETING COLON CANCER STEM CELLS
Colon cancer is third most prevalent cancer in the United States, with significant health consequences for the patient and society. Cancer stem cells are believed to be resistant to conventional treatments resulting in ... -
Dementia Risk in Elders with Anxiety and Insomnia
Current evidence suggests that there is an association between benzodiazepine-receptor-agonist medications (BZRA) and subsequent dementia. Expert opinions differ regarding whether the association indicates a causal ... -
Dementia Risk in Elders with Anxiety and Insomnia
Current evidence suggests that there is an association between benzodiazepine-receptor-agonist medications (BZRA) and subsequent dementia. Expert opinions differ regarding whether the association indicates a causal ... -
Descriptions of nurses' experiences with electronic health records (EHR): A phenomenological study
(2008-03-11)The overall goal of this dissertation study was to explore and describe the lived experiences of nurses working with Electronic Health Records (EHR). Since U.S. President Bush’s 2004 mandate to put EHRs in place by 2014, ... -
Descriptive epidemiology and outcome of patients with intraductal papillary mucinous neoplasm (IPMN): a population-based comparison to pancreatic adenocarcinoma and review of literature.
(2009-04-27)Intraductal papillary neoplasm (IPMN) is an uncommon cancer of the pancreas, histologically characterized as a distinct entity by WHO in 1996, as noninvasive (adenoma, borderline neoplasm, carcinoma in situ) or invasive. ... -
Descriptive epidemiology of 2007 homebuilt aircraft accidents and accident and fatality rates
(2009-06-30)Abstract: Homebuilt aircraft are those that the builder has completed at least 51% of the construction themselves. From 1993 National Transportation and Safety Board data, homebuilt aircraft made up only 3% of the flying ... -
Design & implementation of the pilot physician program for the U.S. Air Force - Air National Guard
(2008-04-18)This paper outlines a proposal to develop and implement a plan that will establish a pilot-physician program for the entire USAF Air National Guard – thus tapping an available, but unutilized resource. Specific aims of ... -
Design and Construction of an Anti-HIV Protease Transducer
Current therapies against HIV, mainly the highly active anti-retroviral therapy (HAART), concentrate on reducing the viral load and recovering CD4 levels, however they are faced with a rebound of HIV levels on cessation ... -
Design, Synthesis, and Pharmacological Characterization of Serotonin (5-HT) 5-HT2C Receptor (5-HT2CR) Positive Allosteric Modulators
A decreased signaling capacity at the serotonin (5-HT) 5-HT2C receptor (5-HT2CR) regulates neurobehavioral processes that may underlie chronic health issues such as impulsivity disorders, drug addiction, depression, ... -
Determining the Efficacy of an Interprofessional Educational Intervention for Teamwork Competencies with Nursing Students
Interprofessional education (IPE) is recognized widely as an essential component to improving patient outcomes but little progress has been made toward understanding the impact of specific educational interventions on ... -
Developing individualized ground testing protocols for use of sleep medications in spaceflight
(2010-05-18)During spaceflight, sleep time are markedly reduced for astronauts. Sleep medications are used by astronauts during space mission for sleep. Spaceflight is an environment where abrupt alarm awakening is always a possibility ... -
Developing Methods to Study Pathogenesis and Immune Response to HSV-2 in the Guinea Pig Model
In order to develop an effective vaccine for HSV-2 it is important to adequately understand the immune response in the proper animal model. Guinea pigs fully recapitulate human HSV-2 disease, but reagents and assays available ... -
Developing Methods to Study Pathogenesis and Immune Response to HSV-2 in the Guinea Pig Model
In order to develop an effective vaccine for HSV-2 it is important to adequately understand the immune response in the proper animal model. Guinea pigs fully recapitulate human HSV-2 disease, but reagents and assays available ... -
Development and Implementation of a Health Literacy Program in a Community Primary Care Clinic in Houston, Texas
Literacy is the way in which our society is able to express ideas and have them understood by others. Without literacy, and particularly health literacy, individuals cannot become full participants in managing their own ... -
Development and Implementation of a Sustainable Monitoring and Evaluation Protocol for a Malnutrition Rehabilitation Program in a Resource-Limited Setting
Worldwide, nearly 7 million children die each year and malnutrition contributes to almost half of these cases. Malnourished children have lower life expectancy, perform worse in school, and are at increased risk for ... -
Development and Utilization of a Bioengineered 3D Human Lung Model to Study Pathogenesis of Lung Disease
There is a great need for research models that mimic human lung physiology and lung pathologies such as chronic lung diseases and respiratory infections. The morbidity and mortality associated with lung disease and ... -
Development and Utilization of Novel Immunologic Reagents for Infectious Disease Studies in the Guinea Pig
Genital herpes disease caused by HSV-2 infections is a worldwide public health epidemic with a global prevalence estimated at 500 million. These individuals serve as a reservoir for transmission of the virus to naïve ...