Browsing Published ETD Collection by Title
Now showing items 175-194 of 499
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Gastrin-releasing peptide-mediated neuroblastoma growth: A role for the PI3K/Akt pathway
(2008-12-18)Neuroblastoma is the most common extracranial solid tumor in infants and children. Our lab and others have shown trophic actions of gastrin-releasing peptide (GRP), and its analogue bombesin (BBS), in neuroblastomas. Our ... -
Gene expression microarray analysis of small, purified cell subsets
(2007-04-23)Gene expression microarray technology is potentially capable of examining all of the cellular processes at the mRNA level at a given moment. One major challenge in its applicability is that most biological samples are cell ... -
General physical preparedness of emergency and essential personnel
(2010-07-12)Emergency and disaster preparedness plans are an essential requirement for most organizations today due to the frequency and complexity of incidents such as disease outbreaks, natural disasters such as hurricanes, floods, ... -
A general scaffold for the synthesis of cysiherbaine and its analogues
(2008-12-03)Dysiherbaine 1 and a select number of structurally related compounds have been shown to have selective effects on ionotropic glutamate receptors (iGluRs). iGluRs are essential components in the central nervous system (CNS); ... -
Genetic Determinants of Junin Virus Attenuation
The New World arenavirus Junin (JUNV) is the causative agent of the Argentine hemorrhagic fever (AHF), a deadly disease endemic to central regions of Argentina. The live-attenuated Candid #1 strain of JUNV is currently ... -
Genetic determinants of NEIL2 transcription
(2008-03-20)The human genome is constantly damaged by reactive oxygen species (ROS) which produce a multitude of oxidative DNA lesions that can lead to mutations, genomic instability, and ultimately, to the development of cancer and ... -
Genetic diversity and taxonomical relationships among the tacaribe serocomplex viruses (family arenaviridae)
(2007-05-30)The three objectives of this dissertation were to 1) examine the natural host relationships and origins of the North American Tacaribe serocomplex viruses (family Arenaviridae), 2) extend our knowledge of the genetic ... -
Genotypic and Phenotypic Determinants of Japanese Encephalitis Virus Geographical Expansion
Japanese encephalitis virus (JEV) consists of at least four geographically and epidemiologically distinct genotypes (GI-IV). Genotypes II and IV have been isolated in tropical Asia only, and GI has recently replaced GIII ... -
Giving voice to the vulnerable: Advocacy and oncology nursing
(2008-07-24)Despite common use of the term, there is no consensus among nursing professionals on a definition of advocacy, how to teach it, measure it, and determine its effectiveness. The purpose of this grounded theory study was to ... -
Global Health, Social Justice, and Corporate Accountability
Chapter one of the dissertation contrasts libertarian theories to the theories of John Rawls and the human development approach favored by Martha Nussbaum and Amartya Sen. Libertarian theorists such as Robert Nozick, Murray ... -
GOUT: An aeromedical clinical practice guideline
(2008-04-21)Through the completion of this capstone project, I am demonstrating the significance of gout in the United States of America, and in particular in the arena of aerospace medicine today. I have created a current clinical ... -
A grounded theory study of substance use patterns among homeless youth
(2009-07-13)A Grounded Theory Study of Substance Use Patterns among Homeless Youth\r\n\r\nPublication No.______________\r\nPhilisie Starling Washington, PhD\r\nThe University of Texas Medical Branch, 2009\r\n\r\nSupervisor: Carolyn ... -
Growth Factors Up-Regulate Epithelial Stem Cells: Treatment Strategies for Colorectal Cancers
Colorectal-cancer is a leading cause of cancer deaths in United States. Accumulating evidence suggests that elevated progastrins (PG) increase the risk of colon carcinogenesis, however mechnaims involved remain ill-defined. ... -
Health Promotion for the Community Advocate
The aim of this capstone is to review social and behavioral factors relevant to health promotion for obesity and chronic diseases in impoverished communities. Obesity and chronic diseases have displaced infectious diseases ... -
Hearing assessment aboard the International Space Station
(2010-09-15)This study undertakes to refine the understanding of the accuracy of a novel PC-based hearing assessment utilized aboard the International Space Station. During the design and construction of the ISS, time and funding ... -
Helicase-Initiated Assembly of Macromolecular Machines Involved in DNA Replication
The research goal of this project is to obtain the first, comprehensive, physical model of the initial phase of the PriA helicase-directed formation of the primosome, a large protein-DNA complex, in E. coli, responsible ... -
Helicobacter pylori Type 4 Secretion System Modulates Host T Cell Responses
Infection with Helicobacter pylori (H. pylori) bacteria is associated with gastritis, peptic ulcer, and gastric cancer. During H. pylori infection CD4+ T cells in the gastric lamina propria are hyporesponsive and polarized ... -
HEM-protein regulates cell migration and asymmetric cell division during development of the ventral nerve cord in Drosophila melanogaster
(2010-07-08)Cell migration and asymmetric cell division are two of the key events during development of the nervous system. I have focused on a typical neuronal lineage, NB4-2→GMC-1→RP2/sib, in the ventral nerve cord (VNC) of the ... -
Histopathological and Molecular Changes in Intestinal Tissue Following Proton Exposure in Varying Mouse Models
Most people are aware that radiation can have negative health consequences for human beings exposed to the phenomena. These negative outcomes are dependent upon dose, dose rate, the individual’s genetic makeup and other ... -
Hospital and Medical Care Days in Pancreatic Cancer
Background: Little is known about resource utilization (number of days in the hospital or medical care) between diagnosis and death in patients with pancreatic cancer. Methods: Using Surveillance, Epidemiology, and End ...