Browsing Published ETD Collection by Title
Now showing items 202-221 of 499
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\"ICE\" awareness among local EMS personnel
(2008-07-10)‘ICE’ stands for ‘in case of emergency.’ The ICE concept is simply to have people program their emergency contact information into their cell phone contact list under the acronym ‘ICE.’ In this way rescuers on a scene ... -
Identificaiton of the pore-lining helices of connexin 43 gap-junctional hemichannels
(2008-03-28)The gap-junctional channels that mediate intercellular communication are formed by head-to-head docking of two gap-junctional hemichannels from adjacent cells. The hemichannels are hexamers of connexins, proteins that have ... -
Identification and characterization of cell-adapted mutations in West Nile Virus and replicons
(2007-12-19)Flavivirus persistence in cell culture is achieved by altering the interaction between the viral genome and the host cell. To identify some of the factors that contribute to a persistent West Nile virus (WNV) infection, ... -
Identification and Characterization of Effectors/Binding Molecules for the Small GTPase Rab15
(2005-03-18)Endocytic trafficking is a key mechanism for regulating receptor availability on\r\nthe plasma membrane as well as receptor degradation. Clathrin-dependent endocytosis\r\ninvolves receptor internalization into early ... -
Identification of protective rickettsial antigens for vaccine development
The genus Rickettsia contains some of the most lethal pathogens known to man, including Rickettsia prowazekii, a select agent that could be used as a biological weapon. Although Rickettsia spp. cause important diseases ... -
If walls could talk: The lived experience of witnessing verbal abuse toward residents in long-term care facilities.
(2007-10-19)Twenty percent of the population over 65 years of age will spend some time in a nursing home. Most research addressing abuse in long-term care (LTC) facilities focus on sexual abuse, physical abuse and financial abuse or ... -
IL-1 activation of NF-kB contributes to perinatal hypoxia/ischemia induced cell death
(2005-06-01)IL-1 activity has been implicated in perinatal hypoxia/ischemia (HI) brain damage without the underlying mechanisms being characterized. We used a 7-day-old rat model to elucidate the role of NF-kB in HI stimulation of ... -
IL-10 Deficiency as a Factor in Airway Cellular Responses to Inhaled Sulfur Dioxide
Sulfur dioxide (SO2) is a problem air pollutant in areas of widespread industrialization, not only in the United States, but also in countries undergoing rapid industrialization, such as China. Thus, air pollution and its ... -
Image-Based Biomarkers in Retinal Disease: Applications in Macular Degeneration
The purpose of this research was to investigate and objectively quantify image-based biomarkers of ocular injury and disease using a combination of non-invasive high resolution imaging techniques. High resolution imaging ... -
Immunomodulation in Adenovirus-Induced Viral Hepatitis
Many viruses can infect the liver and persist there as their site of primary infection. The clinical outcomes in viral hepatitis can range from complete pathogen clearance and recovery of liver function to failure to contain ... -
Immunopathogenic mechanisms of non-healing cutaneous leishmaniasis caused by Leishmania amazonensis infection
(2007-04-10)The objective of my dissertation project is to understand mechanisms employed by Leishmania amazonensis to evade host immune components, particularly B cells and interferon-gamma. Our data have shown that L. amazonensis ... -
Impact of Diabetes Comorbidity on Health Outcomes in Patients Undergoing Medical Rehabilitation after Lower Extremity Joint Arthroplasty
(2013-06-03)Introduction: Diabetes is one of the rapidly increasing chronic conditions that can impact the health and well-being of individuals. Objectives: To determine the prevalence of diabetes in patients receiving medical ... -
Impact of genetic variability in the serotonin transporter, Tryptophan Hydroxylase-2, and Serotonin 2A Receptors on MDMA Use and Impulsivity
(2008-08-19)Ecstasy [MDMA; (±)-3,4-methylenedioxymethamphetamine] is popular for positive effects including enhanced mood and empathy, despite potential deleterious physical and psychological consequences. The serotonin (5-HT) system ... -
Impact of Peer Observation on Learning Outcomes in Simulated Clinical Learning Experiences
Comparison of traditional teaching methods with simulation in nursing education research fails to inform educators on how to best design, structure and implement simulation experiences to improve student learning outcomes. ... -
The impact of protein fluctuations on molecular recognition
(2008-12-05)The effect of protein fluctuations on molecular recognition is poorly understood. Prediction of useful properties such as binding affinity using rigid structures has produced sporadic success. Although attempts have been ... -
The impact of race/ethnicity on post acute services
(2009-02-24)Each year, more than 300,000 people fracture their hip. The number of hip fractures in the US is expected to increase with the aging of the population in the coming years; by 2040, 500,000 patients annually will sustain ... -
Impact of West Nile Virus Envelope Domain III Surface Loop Residues on Antigenicity and Virulence
West Nile virus (WNV) is an encephalitic flavivirus that is maintained worldwide in a transmission cycle between birds and mosquitoes. Domain III of its envelope protein is the target of highly specific and potently ... -
Important role of the type VI secretion system in the virulence of an emergent human pathogen Aeromonas hydrophila: Delineating the mechanism of action of its effectors
(2010-07-02)Aeromonas hydrophila causes various human diseases, including gastroenteritis, wound infections and septicemia. In this study, we characterized the new type 6 secretion system (T6SS) from isolate SSU of A. hydrophila and ... -
In hospital functional assessments in the elderly and their association to post discharge health outcomes
(2008-06-24)The purpose of this study was to investigate the functional status of a sample of older adults during hospitalization for acute illness and to examine associations between functional status measures assessed during ... -
Individual sensitivity to novelty and (+)-3,4-methylenedioxymethamphetamine: Roles for serotonin and GABA neurotransmission
(2005-01-27)Drug addiction continues to be a problem in our society, and better understanding of the neuroanatomical and neurochemical alterations that delineate the switch between causal drug use and compulsive drug addiction is ...