Browsing Published ETD Collection by Title
Now showing items 446-465 of 741
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The nanomechanics of polycystin-1: A kidney mechanosensor
(2010-06-25)Mutations in polycystin-1 (PC1) can cause Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is a leading cause of renal failure. The available evidence suggests that PC1 acts as a mechanosensor, receiving signals ... -
Natural causes: Do physicians code for uncertainty In cause of death?
(2010-05-18)Cause of death (COD) determination by physicians on the death certificate can be difficult when the conditions leading to death are unclear or uncertain. The Center for Disease Control (CDC) recommends the classification ... -
Near infrared light to promote synaptic resilience to Alzheimer’s Disease neuropathology
Alzheimer’s Disease (AD) is a multifactorial neurodegenerative dementia with no curative therapeutic options. One of the earliest impairments in AD triggering cognitive decline is the synaptic dysfunction induced by the ... -
Near-Infrared Light Reduces Glia Activation and Modulates Neuroinflammation in Brain of Diet-Induced Obese Mice
Obesity is one of the most prominent risk factors for Alzheimer’s Disease (AD); obesity and AD share several pathological features, in particular the neuroinflammation. Hippocampal neuroinflammation, in rodents, correlates ... -
Neuromedin U Acts via the Paraventricular Nucleus of the Hypothalamus and the Dorsal Raphe Nucleus to Regulate Motivation for High-Fat Food
Motivation for high-fat food is thought to contribute to excess caloric intake in obese individuals. A novel regulator of motivation for food may be neuromedin U (NMU), a highly-conserved neuropeptide that influences food ... -
Neuronal and Vascular Degeneration of the aging retina in the 3xTg-AD mouse
Alzheimer's disease (AD), a progressive and irreversible neurodegenerative disease and the most common cause of dementia in the United States, is characterized by amyloid β (Aβ) and tau deposition in the central nervous ... -
Neutrophil interactions with Leishmania amastigotes: implications for chronic leishmaniasis
Leishmaniasis is a neglected tropical disease responsible for considerable morbidity and mortality in the developing world. The immune response against Leishmania parasites must be fine-tuned to promote pathogen clearance ... -
Neutrophil Regulation of Colitis
The delicate intestinal homeostasis is regulated by interactions between microbiota, intestinal epithelial cells (IECs), and the intestinal immune system. As a crucial component of the innate immune system, neutrophils are ... -
New Insights Regarding the Intracellular Effects, Trafficking, and Quality Control of the Amyloid Precursor Protein: Implications for Alzheimer’s Disease Pathogenesis
Alzheimer’s disease (AD) is the most common form of age-related dementia. Our current understanding of AD pathogenesis is largely based on data from cases of relatively rare early-onset forms of the disease, collectively ... -
New virulence mechanisms in Yersinia pestis, the plague (Black Death)-causing bacterium: A re-emerging and bioterror pathogen
(2009-03-24)Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. Y. pestis is also a category A select agent based on its potential use as a biological weapon. Currently, ... -
NICU Nurses’ Attitudes Regarding Preterm Infant Massage
When preterm infants are admitted in the NICU, mothers report experiencing uncertainty; powerlessness; loss of control; role alterations; fears to hold, feed, or touch the newborn; feelings of intrusion; and alienation in ... -
NMR Studies on Kinetics of Processes Involving DNA-Binding Proteins
Macromolecular interactions do not just encompass the coming together of two or more macromolecules, but rather the speed of the interactions play a very important role in proper cellular function. In response to external ... -
NMR Studies on Protein Dynamics and Its Relevance to Functional Kinetics.
Existence of a strong relationship between protein's dynamics and its functional kinetics was suggested decades ago. Even though different groups investigated this relationship, technical difficulties and lack of appropriate ... -
"No One Died Today:" A Naturalistic Inquiry into the Perceptions and Experiences of School Nurses Dealing with Adolescents who Self-Harm
There is an increased incidence of self harm among middle and high school age adolescents. The school nurse (SN) is in a position to recognize this behavior (Cooke & James, 2009), but little is known about the school nurse’s ... -
¡No Smoking Por Vapor! Systematic Literature Review Examining the Attitudes Toward, Beliefs About, Perceived Risks and Benefits of Electronic Cigarettes and Toward Their Use Among United States Youth
Electronic cigarettes are an emerging topic of discussion and debate in Public Health. Their ability to deliver nicotine in the form of vapor gave rise to the idea of electronic cigarettes being used as nicotine replacement ... -
Non-conventional Regulation of Treg Development and Function
IBD is a serious, lifelong illness that is both debilitating and financially costly. There are few effective pharmaceuticals for IBD, and many patients ultimately require surgical treatment. Hence, the development of new ... -
Non-invasive Optoacoustic Monitoring of Neonatal Cerebral Venous Oxygen Saturation
Peripartum asphyxia is a common cause of cerebral hypoxia and when severe can lead to neuronal injury and hypoxic-ischemic encephalopathy (HIE) in the newborn. HIE has been reported up to 3/1000 live births with a high ... -
The nongenomic effects of physiological and environmental estrogens on dopamine transporter function
(2008-12-01)Neurological diseases and neuropsychiatric disorders that vary depending on female life stages suggest that sex hormones may influence the function of neurotransmitter regulatory machinery such as the dopamine transporter ... -
Noninvasive optoacoustic monitoring of blood oxygenation in large blood vessels
(2007-09-19)Continuous monitoring of cerebral blood oxygenation is critically important for successful treatment of patients with severe traumatic brain injury and patients undergoing cardiac surgery. At present, the techniques for ... -
Nonprofit Hospital Community Benefits: The Effect of Needs Assessment Quality and Monetary Input on Health Outcomes.
Nonprofit hospitals in the United States are expected to give back to their communities and promote healthy living. In return for providing community services they are recognized as charity organizations and awarded tax ...