Browsing Published ETD Collection by Title
Now showing items 299-318 of 499
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The nanomechanics of polycystin-1: A kidney mechanosensor
(2010-06-25)Mutations in polycystin-1 (PC1) can cause Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is a leading cause of renal failure. The available evidence suggests that PC1 acts as a mechanosensor, receiving signals ... -
Natural causes: Do physicians code for uncertainty In cause of death?
(2010-05-18)Cause of death (COD) determination by physicians on the death certificate can be difficult when the conditions leading to death are unclear or uncertain. The Center for Disease Control (CDC) recommends the classification ... -
Neutrophil interactions with Leishmania amastigotes: implications for chronic leishmaniasis
Leishmaniasis is a neglected tropical disease responsible for considerable morbidity and mortality in the developing world. The immune response against Leishmania parasites must be fine-tuned to promote pathogen clearance ... -
New Insights Regarding the Intracellular Effects, Trafficking, and Quality Control of the Amyloid Precursor Protein: Implications for Alzheimer’s Disease Pathogenesis
Alzheimer’s disease (AD) is the most common form of age-related dementia. Our current understanding of AD pathogenesis is largely based on data from cases of relatively rare early-onset forms of the disease, collectively ... -
New virulence mechanisms in Yersinia pestis, the plague (Black Death)-causing bacterium: A re-emerging and bioterror pathogen
(2009-03-24)Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. Y. pestis is also a category A select agent based on its potential use as a biological weapon. Currently, ... -
NICU Nurses’ Attitudes Regarding Preterm Infant Massage
When preterm infants are admitted in the NICU, mothers report experiencing uncertainty; powerlessness; loss of control; role alterations; fears to hold, feed, or touch the newborn; feelings of intrusion; and alienation in ... -
NMR Studies on Kinetics of Processes Involving DNA-Binding Proteins
Macromolecular interactions do not just encompass the coming together of two or more macromolecules, but rather the speed of the interactions play a very important role in proper cellular function. In response to external ... -
NMR Studies on Protein Dynamics and Its Relevance to Functional Kinetics.
Existence of a strong relationship between protein's dynamics and its functional kinetics was suggested decades ago. Even though different groups investigated this relationship, technical difficulties and lack of appropriate ... -
¡No Smoking Por Vapor! Systematic Literature Review Examining the Attitudes Toward, Beliefs About, Perceived Risks and Benefits of Electronic Cigarettes and Toward Their Use Among United States Youth
Electronic cigarettes are an emerging topic of discussion and debate in Public Health. Their ability to deliver nicotine in the form of vapor gave rise to the idea of electronic cigarettes being used as nicotine replacement ... -
Non-conventional Regulation of Treg Development and Function
IBD is a serious, lifelong illness that is both debilitating and financially costly. There are few effective pharmaceuticals for IBD, and many patients ultimately require surgical treatment. Hence, the development of new ... -
The nongenomic effects of physiological and environmental estrogens on dopamine transporter function
(2008-12-01)Neurological diseases and neuropsychiatric disorders that vary depending on female life stages suggest that sex hormones may influence the function of neurotransmitter regulatory machinery such as the dopamine transporter ... -
Noninvasive optoacoustic monitoring of blood oxygenation in large blood vessels
(2007-09-19)Continuous monitoring of cerebral blood oxygenation is critically important for successful treatment of patients with severe traumatic brain injury and patients undergoing cardiac surgery. At present, the techniques for ... -
Novel Effects of Simvastatin on Uterine Fibroids
Uterine fibroids (also known as leiomyomas) represent a common gynecologic problem with a significant medical and economic burden. Unfortunately, no satisfactory long-term medical treatment is currently available. Statins ... -
Novel Insights Into Normal Aryl Hydrocarbon Receptor Biology Through the Regulation of Stanniocalcin 2
(2013-06-03)Proper hepatocyte function is vital for survival; hence unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver ... -
Obesity, Diabetes, and Disability in Older Mexican Americans, 1993-2011
Increases in obesity have been observed in both men and women, for all age groups and major ethnic groups, and at all educational levels. However, in Mexican Americans, the increased level of obesity only partially accounts ... -
On Being A NASA Flight Surgeon
Flight surgeons are physicians that care for the varied medical needs of aviators, flyers, pilots and astronauts. This thesis constitutes a literature review as to the characteristics of flight surgeons including from a ... -
Organ Donation in the United States
(2013-06-03)Introduction: The demand for donor organs far exceeds the number of donors. Approximately 18 people in the United States die every day waiting for an organ transplant. The purpose of this capstone is to describe the ... -
Overuse of 3 Common Tests in the Elderly: Primary Care Physician (PCP) Variation, Associated Physician Characteristics, and Correlation of Overuse of Tests Within Physicians
Overuse of tests in the elderly is a nationwide problem that leads to patient harm. Some of the most commonly ordered tests are overused even though specific guidelines have been published and appropriately disseminated. ... -
Oxygen resuscitation does not ameliorate neonatal hypoxia/ischemia-induced edema
(2009-03-20)Neonatal hypoxia/ischemia (HI) is the most common cause of developmental neurological, cognitive and behavioral deficits in children. Although cerebral edema is a common outcome after HI, the mechanisms leading to the ... -
Parasite interactions with dendritic cells and macrophages: Implications for cutaneous Leishmaniasis caused by Leishmania amazonensis
(2003-03-26)Protozoan Leishmania is an important human pathogen that affects millions people worldwide. Investigation of experimental Leishmania infection in mice has been instrumental to our understanding of interactions between the ...