Browsing Published ETD Collection by Title
Now showing items 430-449 of 499
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Taser subjects: Identification of high-risk individuals
(2008-04-21)Taser® devices are used by many police forces as a nonlethal means of subduing individuals. These devices use conducted electrical energy to cause neuromuscular incapacitation. Tasers have been associated with adverse ... -
TDP-43 and its role in neurodegeneration
Ubiquitinated TDP-43 (TAR DNA Binding Protein) inclusions are a hallmark of ALS (amyotrophic lateral sclerosis) and FTLD-TDP-43 (frontotemporal lobar degeneration with ubiquitin inclusions). These diseases share a similar ... -
The Anti-Inflammatory Effects of Low Concentrations of Carbon Monoxide in Human Airway Smooth Muscle Cells
Carbon monoxide (CO) has emerged as a potential therapy exerting cytoprotective effects in models of inflammatory diseases including asthma. Similar studies implicate human airway smooth muscle cells (HASMC) as contributing ... -
The development of a reverse genetics system for Machupo virus
The etiologic agent of Bolivian hemorrhagic fever (BHF), Machupo virus (MACV), is a highly lethal viral pathogen with no approved vaccine or therapeutic to limit infection or outbreaks. Following implementation of rodent ... -
The direct effects of estradiol and several xenoestrogens on cell numbers of early- vs. late-stage prostate cancer cells
Prostate cancer is the most common non-cutaneous cancer among men, and diethylstilbestrol (DES) is an estrogen that has been used clinically to combat advanced tumors. Estrogens can indirectly decrease androgen production ... -
The Early Events and Long-Term Effects of Perinatal Cerebral
Neonatal hypoxia-ischemia (HI) affects 60% of low birth weight infants and up to 40% of preterm births. Due to the increasing incidence of preterm and low birth weight infants and the lack of adequate treatment for HI, ... -
The Effect of Human Patient Simulation on Medical-Surgical Nurses’ Self-Efficacy in Cardiac Emergency Management
Over 200,000 in-hospital cardiac arrests (IHCA) occur each year, making code management education and training a priority for first responders within the hospital. Medical-surgical nurses, who are frequently the first ... -
The Effect of Modeled Microgravity and Radiation on Epstein-Barr Virus in a Modeled Spaceflight System
Epstein-Barr virus (EBV) is the causative agent of mononucleosis and is also associated with several malignancies, including Burkitt’s lymphoma, Hodgkin’s lymphoma, nasopharyngeal carcinoma, and post-transplant lymphoproliferative ... -
The Effect of Obesity on Disability and Mortality in Mexican Older Adults
(2016-04-29)Objective: To examine the effect of obesity on incidence of disability and mortality among non-disabled older Mexicans at baseline. Methods: The sample included 8,415 Mexicans aged ≥50 years from the Mexican Health and ... -
The effect of repetitive subconcussive head impacts on observed physiological, biochemical, and functional perturbances in the brain in high school and collegiate football players: a systematic literature review
In this review, we investigated the effects of repetitive subconcussive helmeted head impacts (RSHI) in high school and collegiate athletes. We performed a literature review of all English-language medical literature from ... -
The Effects of Dendro[60]Fullerene on Neurobehavioral Outcome and Cerebral Vascular Function After Traumatic Brain Injury
Traumatic brain injury (TBI) causes an increase in reactive oxygen species (ROS) that leads to cerebral vascular dysfunction. The reduction of ROS can preserve vascular function and lead to improved outcomes. The antioxidant ... -
The Effects of Recorded Music Therapist’s Singing Voice and Recorded Mothers’ Singing Voice on the Transition Preterm Infants from Incubator to Open Crib
A majority of preterm, very low birth weight, and low birth weight infants is thought to be deprived of auditory stimulation needed for normal maturation. It is known that preterm infants by 26 weeks gestation perceive and ... -
The encapsidation protein from Lactococcus lactis asccφ28 as a novel system for the study of molecular motors
Motor proteins, molecules capable of converting the cell’s free energy into mechanical work, are prevalent in life. However, despite their pervasiveness, our understanding of these molecular machines remains inadequate. ... -
The Eosinophil Granular Leukocyte; Source and Target of High Mobility Group Protein B1
Eosinophils are associated with various inflammatory diseases in which they participate through the release of mediators. Eosinophils thereby function as effectors and immunoregulators and contribute to inflammation-associated ... -
The Host Response to Venezuelan Equine Encephalitis Virus
Viruses are currently the most common cause of encephalitis. Arboviruses in the Alphavirus genus in the family Togaviridae contain multiple viruses capable of causing human encephalitis. Of these, VEEV represents the most ... -
The Impact of Methamphetamine on Genital Herpes Disease Pathogenesis and Host Immune Responses to Herpes Simplex Virus Type 2 in Mouse and Guinea Pig Models
Use of the stimulant methamphetamine (METH) is increasingly common, with over 35 million users worldwide. There is a known association between stimulant use and an increased incidence of HIV and other sexually transmitted ... -
The Impact of the Non-Structural Small Segment Gene on Host Immune Responses Against Rift Valley Fever Virus
Rift Valley fever virus (RVFV) is responsible for large periodic outbreaks of enzootic hepatitis of ruminants. Inevitably, due to the close proximity and relationship between, the mosquito vector species, livestock, and ... -
The invasin IbeA and its role in Adherent-Invasive Escherichia coli (AIEC) pathogenesis
In this study, an Adherent-Invasive Escherichia coli (AIEC) ∆ibeA mutant was constructed and characterized, and its effect on AIEC adhesion and invasion of intestinal epithelial cells evaluated. The role that this outer ... -
The Journey of Men in Nursing: A Critical Ethnography
Patient health outcomes are linked to the quality of nursing care, which in turn is linked to adequacy of nurse staffing. Changing population and nurse demographics are anticipated to exacerbate the current nursing shortage. ... -
The Lived Experience of Emergency Service Personnel in Pediatric Resuscitation and Unexpected Death: A Phenomenological Study
There were over 63,000 pediatric deaths in the United States in 2013, with almost 7,000 of those deaths attributed to accidental causes, homicide, and suicide. The death of a child has a major impact on healthcare professionals ...