Browsing Published ETD Collection by Title
Now showing items 168-187 of 746
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Diabetes and obesity as risk factors for the development of Hepatocellular carcinoma in the hispanic population
(2008-12-08)Hepatocellular carcinoma is the fifth most prevalent cancer in the world with an overall 5-year survival rate of 6.9%. The well known etiological factors for HCC are infection with hepatitis B virus (HBV) and hepatitis C ... -
Diabetes mellitus in U.S. aviators
(2009-04-02)Introduction: This project summarizes current information on the risks associated with diabetes mellitus and its medical management amongst aviation personnel. Methods: A literature review was accomplished looking at ... -
Diabetes, diabetes complications, and their consequences in Mexican-American elders
(2007-06-22)The purpose of this study is to describe the epidemiology of diabetes, diabetes complications and their consequences over an 11-year period in Mexican-American elders. Design: This is an 11-year prospective cohort study ... -
Differences in miR-122 and miR-191 Expression in HBV- versus HCV-associated Hepatocellular Carcinoma
Prior studies have suggested that the expression of miR-122 and miR-191 is decreased and increased, respectively, in hepatocellular carcinoma. However, other evidence suggests miR-122 may be preserved in HCV-associated ... -
Differences in Pediatric Unintentional Injury Outcomes by Race/Ethnicity
Unintentional injuries contribute significantly to childhood mortality and morbidity nationally and globally. In the United States, they are the leading cause of death in children over the age of 1, causing more than 9,000 ... -
Differential mechanisms by which the aryl hydrocarbon receptor attenuates liver regeneration
(2007-10-11)Liver regeneration is orchestrated by a series of autocrine and paracrine cues that function to restore hepatic tissue, however the precise cellular and molecular mechanisms that regulate these signaling events are poorly ... -
“Differential regulation of PTHrP gene expression by 1,25(OH)2D3 in prostate cancer cell lines”
(2005-07-08)Parathyroid hormone-related protein (PTHrP) is expressed by prostate cancer cells. Since PTHrP enhances the growth and osteolytic potential of prostate cancer cells, it is important to control PTHrP expression in these ... -
Disaster relief: Fatugue and countermeasures
(2007-09-04)The emphasis of this paper has been to educate disaster leaders on fatigue and fatigue management. The need for sleep is real, inescapable and often misunderstood. The impact of fatigue on performance is greatly magnified ... -
Discovering Dengue Drugs-Together: Grid Scale Virtual Screening with Mean Field Free Energy of Binding Rescoring
(2011-09-27)The virtual screening of chemical databases against drug discovery targets with docking programs can enrich a database for bioactive compounds. However, current virtual screening methods generate many false positives ... -
Discovering Dengue Drugs-Together: Grid Scale Virtual Screening with Mean Field Free Energy of Binding Rescoring
(2011-09-27)The virtual screening of chemical databases against drug discovery targets with docking programs can enrich a database for bioactive compounds. However, current virtual screening methods generate many false positives ... -
Discovering the Current Wound Management Practices of Rural Africans: a Pilot Study
(2013-06-03)Unrelenting heat, poor sanitation, lack of knowledge, and poverty contribute to a disabling wound prevalence that often exceeds 20% in rural areas of tropical developing countries. Wounds in this environment are usually ... -
Discovery and characterization of a newly emerged DENV serotype.
Dengue virus (DENV) is a mosquito-transmitted flavivirus that presents a substantial threat to public health worldwide. One third of the global population is at risk of infection and over 400 million cases of dengue are ... -
Disruption of Immunoregulatory Functions of Intestinal Mesenchymal Stromal Cells and their Progenitors in Inflammatory Bowel Disease
Crohn’s Disease (CD) and Ulcerative Colitis (UC), the two major forms of Inflammatory Bowel Disease (IBD), are multifactorial autoimmune diseases caused by an abnormal immune response to gut microbiota in genetically ... -
DISRUPTION OF THE HIPPOCAMPAL GABAERGIC SYSTEM IN THE Fgf14 ̶ / ̶ MOUSE MODEL
In CNS, cognitive function is greatly dependent on the functional integrity of gamma-amino-butyric acid (GABA) interneurons. These inhibitory interneurons modulate synaptic plasticity and intrinsic excitability of principal ... -
Distribution and targeting of CLC-3
(2006-11-06)ClC-3 is a ubiquitously expressed chloride channel that is present in synaptic vesicles and endosome/lysosome compartments. The channel is largely intracellular, but has been observed at the plasma membrane as well. The ... -
Dithioated Phosphates in DNA Duplex Thermodynamics and Protein-DNA Interactions
Phosphorodithioated DNA contains sulfur atoms at both non-bridging phosphoryl oxygen positions. As an achiral chemical modification of the internucleotide linkage it imparts altered biophysical properties to the phosphate ... -
Do condom and needle exchange provision in prisons reduce risky behavior and HIV transmission? A systematic literature review
Prison populations worldwide are disproportionately affected by HIV/AIDS. In the United States alone, the number of inmates with confirmed AIDS is more than two times that of the general population. Furthermore, about one ... -
Does Context Matter to ACEs? The Role of State Economic Context and Selected State Policies in Childhood Adversity
Childhood adversity is a widespread public health problem in the United States. Half of adults experienced at least one serious adversity during childhood, and a quarter experienced two or more. Childhood adversity, often ... -
Dopamine-induced synaptic plasticity in the amygdala in saline-and cocaine-treated animals undergoing conditioned place preference
(2008-11-24)One of the biggest problems facing cocaine addicts is relapse and currently there are no treatments for relapse. These studies will provide insight into the underlying mechanisms of LTP mediating relapse to cocaine. A ... -
Dynamic and kinetic investigations of SEM-5/SOS peptide interactions
(2009-04-01)The dynamics of SEM-5 SH3 domain protein can provide an important insight into how structural dynamics contribute to protein function. This is important because solving the structure of protein alone only provides the ...