Browsing Published ETD Collection by Title
Now showing items 279-298 of 758
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Food Allergy Risk Mitigation in Texas Independent School Districts
An estimated 4%-6% of American school children attending federal, state, early care and education programs are affected by food allergies. Allergic reactions can be life threatening, with resultant far reaching impact on ... -
Fully informed consent: Can public trust be restored and harms avoided?
(2007-07-27)Currently, research with human subjects is going through a period of tremendous upheavals. In many cases these upheavals have created a variety of unmet expectations and have given rise to the perception that trust in the ... -
The function of the hepatitis C virus p7 protein
(2010-08-26)The Hepatitis C Virus is the most common cause of chronic liver disease. Current therapy is only partially effective and fraught with side effects. A greater understanding of viral replication and new virus particle ... -
Functional analysis of glycosylation of Zika virus envelope and NS1 proteins
Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. ZIKV has two important glycoproteins, both the envelope (E) protein, and nonstructural protein 1 (NS1). The ZIKV envelope ... -
Functional analysis of glycosylation of Zika virus envelope and NS1 proteins
Zika virus (ZIKV) infection causes devastating congenital abnormities and Guillain-Barré syndrome. ZIKV has two important glycoproteins, both the envelope (E) protein, and nonstructural protein 1 (NS1). The ZIKV envelope ... -
Functional genomic analysis of PPAR-gamma in human colorectal cancer cells
(2006-12-14)The gamma isoform of peroxisome-proliferator activated receptor (PPAR-gamma) is a member of the super family of nuclear hormone receptors and shows much promise as a chemopreventative and therapeutic target for colorectal ... -
Functional role of GSK3β in p38MAPK mediated human amnion membrane senescence
Oxidative stress (OS) induced stress signaler p38 mitogen-activated protein kinase (p38MAPK) activation and fetal membrane senescence are associated with parturition. Our study determined changes in multipotent pro-cell ... -
Gastrin-releasing peptide-mediated neuroblastoma growth: A role for the PI3K/Akt pathway
(2008-12-18)Neuroblastoma is the most common extracranial solid tumor in infants and children. Our lab and others have shown trophic actions of gastrin-releasing peptide (GRP), and its analogue bombesin (BBS), in neuroblastomas. Our ... -
Gene expression microarray analysis of small, purified cell subsets
(2007-04-23)Gene expression microarray technology is potentially capable of examining all of the cellular processes at the mRNA level at a given moment. One major challenge in its applicability is that most biological samples are cell ... -
General physical preparedness of emergency and essential personnel
(2010-07-12)Emergency and disaster preparedness plans are an essential requirement for most organizations today due to the frequency and complexity of incidents such as disease outbreaks, natural disasters such as hurricanes, floods, ... -
A general scaffold for the synthesis of cysiherbaine and its analogues
(2008-12-03)Dysiherbaine 1 and a select number of structurally related compounds have been shown to have selective effects on ionotropic glutamate receptors (iGluRs). iGluRs are essential components in the central nervous system (CNS); ... -
Generation and Characterization of Flavivirus Receptor-Binding Domain Mutants and Chimeras
Flaviviruses are positive-sense, single-stranded RNA viruses responsible for millions of infections annually. Primarily transmitted by ticks and mosquitoes, their associated diseases range from mild febrile infections to ... -
Genetic Determinants of ABCB1 Promoter Activity and Their Effects on Environmental Exposure
In utero exposure to xenobiotics, including medications and environmental agents, can lead to developmental and behavioral problems as well as cancer later in life. Efflux transporters, which are highly expressed in the ... -
Genetic Determinants of Junin Virus Attenuation
The New World arenavirus Junin (JUNV) is the causative agent of the Argentine hemorrhagic fever (AHF), a deadly disease endemic to central regions of Argentina. The live-attenuated Candid #1 strain of JUNV is currently ... -
Genetic determinants of NEIL2 transcription
(2008-03-20)The human genome is constantly damaged by reactive oxygen species (ROS) which produce a multitude of oxidative DNA lesions that can lead to mutations, genomic instability, and ultimately, to the development of cancer and ... -
Genetic diversity and taxonomical relationships among the tacaribe serocomplex viruses (family arenaviridae)
(2007-05-30)The three objectives of this dissertation were to 1) examine the natural host relationships and origins of the North American Tacaribe serocomplex viruses (family Arenaviridae), 2) extend our knowledge of the genetic ... -
Genotypic and Molecular Determinants in the Continued Evolution of West Nile Virus in the United States
Following the introduction of West Nile virus (WNV) into New York in 1999, the virus continues to evolve in the U.S. with the emergence, extinction, and co-circulation of multiple, distinct U.S. genotypes. Despite annual ... -
Genotypic and Phenotypic Determinants of Japanese Encephalitis Virus Geographical Expansion
Japanese encephalitis virus (JEV) consists of at least four geographically and epidemiologically distinct genotypes (GI-IV). Genotypes II and IV have been isolated in tropical Asia only, and GI has recently replaced GIII ... -
Giving voice to the vulnerable: Advocacy and oncology nursing
(2008-07-24)Despite common use of the term, there is no consensus among nursing professionals on a definition of advocacy, how to teach it, measure it, and determine its effectiveness. The purpose of this grounded theory study was to ... -
Glia-mediated mechanisms of HIV-1-gp120-induced Synaptic Degeneration
HIV-1 infection of the nervous system causes various neurologic diseases. Synaptic degeneration is a critical underlying neurological pathology. However, the mechanism by which HIV-1 causes synaptic degeneration is unclear. ...