Browsing Published ETD Collection by Title
Now showing items 299-318 of 746
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Group III mGluR8 negatively modulates TRP channels
Several lines of evidence indicate group III metabotropic glutamate receptors (mGluRs) have systemic anti-hyperalgesic effects. We hypothesized this could occur through modulation of TRP channels on nociceptors. The following ... -
Growth Factors Up-Regulate Epithelial Stem Cells: Treatment Strategies for Colorectal Cancers
Colorectal-cancer is a leading cause of cancer deaths in United States. Accumulating evidence suggests that elevated progastrins (PG) increase the risk of colon carcinogenesis, however mechnaims involved remain ill-defined. ... -
Healing at the Margins: A Cultural/Historical Perspective on International Medical Graduates in the US Healthcare System
Foreign, or international, medical graduates make up about twenty five percent of current American medical trainees and twenty percent of physicians actively practicing medicine in the United States. In some specialties, ... -
HEALTH CARE, AGING, AND END OF LIFE: USING COMMUNITY BIOETHICS DIALOGUES TO PROMOTE INDIVIDUALIZED PERSONAL DECISIONS AND ADVANCE CARE PLANNING
In 1976, the New Jersey Supreme Court ruled that Joseph and Julia Quinlan could authorize removal of life support from their comatose daughter. Since that critical ruling, every state has passed legislation allowing ... -
Health Literacy and Psychiatric Hospital Readmissions
This study examined the health literacy of adult patients diagnosed with bipolar disorder, investigated the relationship between health literacy and psychiatric hospital readmissions, identified differences in readmission ... -
Health Promotion for the Community Advocate
The aim of this capstone is to review social and behavioral factors relevant to health promotion for obesity and chronic diseases in impoverished communities. Obesity and chronic diseases have displaced infectious diseases ... -
'Healthcaring': Learning to Resist the Logic of Letting Go through Arts-Based Curriculum in a Student-Run Free Clinic
Contemporary healthcare education does not adequately prepare students for some of the most persistent moral challenges of medical practice in the United States. Healthcare in the US includes practices and policies of ... -
Hearing assessment aboard the International Space Station
(2010-09-15)This study undertakes to refine the understanding of the accuracy of a novel PC-based hearing assessment utilized aboard the International Space Station. During the design and construction of the ISS, time and funding ... -
Helicase-Initiated Assembly of Macromolecular Machines Involved in DNA Replication
The research goal of this project is to obtain the first, comprehensive, physical model of the initial phase of the PriA helicase-directed formation of the primosome, a large protein-DNA complex, in E. coli, responsible ... -
Helicobacter pylori Type 4 Secretion System Modulates Host T Cell Responses
Infection with Helicobacter pylori (H. pylori) bacteria is associated with gastritis, peptic ulcer, and gastric cancer. During H. pylori infection CD4+ T cells in the gastric lamina propria are hyporesponsive and polarized ... -
HEM-protein regulates cell migration and asymmetric cell division during development of the ventral nerve cord in Drosophila melanogaster
(2010-07-08)Cell migration and asymmetric cell division are two of the key events during development of the nervous system. I have focused on a typical neuronal lineage, NB4-2→GMC-1→RP2/sib, in the ventral nerve cord (VNC) of the ... -
HIJACKING OF CELLULAR PATHWAYS BY NOVEL TICK-BORNE PHLEBOVIRUS
Severe Fever with Thrombocytopenia Syndrome (SFTS) virus is an emerging tick-borne Phlebovirus isolated from patients presenting with hemorrhagic manifestations. Case fatality rates of 12-50% have been reported. Limited ... -
Histopathological and Molecular Changes in Intestinal Tissue Following Proton Exposure in Varying Mouse Models
Most people are aware that radiation can have negative health consequences for human beings exposed to the phenomena. These negative outcomes are dependent upon dose, dose rate, the individual’s genetic makeup and other ... -
Hospital and Medical Care Days in Pancreatic Cancer
Background: Little is known about resource utilization (number of days in the hospital or medical care) between diagnosis and death in patients with pancreatic cancer. Methods: Using Surveillance, Epidemiology, and End ... -
Hospital depressive symptoms and ADL disability in older adults: A longitudinal analysis of course and associations
(2010-04-26)Depressive symptoms and disability in activities of daily living (ADL) often increase in older adults during hospitalization and for many persist post-discharge. However, little is known about the psychological and functional ... -
Host cell signaling in response to RSV infection
(2008-04-14)RSV infection is the most important cause of hospitalization of infants, and is also the major cause for admissions in adults with chronic cardiac disease and pulmonary diseases. So far, there is no effective treatment or ... -
Host response of lung cells to virulent Bacillus anthracis
(2008-11-24)Bacillus anthracis, the etiological agent of anthrax, is a Gram-positive, spore-forming bacterium that is classified as a Category A select agent. The current paradigm in anthrax literature labels the alveolar macrophage ... -
Host response to Rift Valley fever virus infection
Rift Valley fever virus (RVFV) has the ability to cause severe disease (in the form of encephalitis or hemorrhagic fever) in humans and animals. RVFV is endemic to parts of Africa and the Arabian Peninsula, but there is ... -
Host-Dependent Expression, Transcriptional Regulation and Protection of Ehrlichia chaffeensis Tandem Repeat Proteins
Ehrlichia chaffeensis is an obligately intracellular bacterium that is the causative agent of human monocytotropic ehrlichiosis, an emerging life-threatening zoonosis. E. chaffeensis is transmitted by the lone star tick, ... -
HUMAN DPP4/CD26 TRANSGENIC MICE AS SURROGATE MODELS FOR MERS
Continued occurrences of the Middle East Respiratory Syndrome caused by a coronavirus (MERS-CoV) and its proven transmissibility among humans constitute an ongoing public health threat. Animal models, especially small ...