Browsing Published ETD Collection by Author "Papaconstantinou, John"
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Molecular Insights and Physiological Consequences of Aryl Hydrocarbon Receptor Regulated Plasminogen Activator Inhibitor-1 Expression
Wilson, Shelly (2013-06-03)The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, attenuates liver regeneration in vivo when activated by its prototypical agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) following 70% partial ... -
Role of TLS Polymerases in Replication of DNA Lesions in Human Cells
Conde Fabela, Juan A; 0000-0003-3252-2463Cells are constantly exposed to numerous genotoxic lesions that inhibit replication. The inability of cells to correctly repair these lesions results in mutations or chromosomal aberrations that threaten the integrity of ...