Risk Factors and Epidemiologic Characteristics of Post Procedural Acute Kidney Injury in Patients from the National Surgical Quality Improvement Program (ACS NSQIP) Participant Use Data File (PUF), 2014


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Acute Kidney Injury (AKI) following surgical procedures puts an enormous burden on the health care system by increasing the length of hospital stay, requiring renal replacement therapy or kidney transplant, and even leading to death. Few studies have been performed to determine the predictive factors for post procedural AKI in general surgery patients. In this study, we investigated the epidemiologic characteristics of, as well as the predictive factors for, post-surgical AKI among the patients in the dataset of American College of Surgeons’ National Surgical Quality Improvement Program (ACS NSQIP) in 2014. We performed univariate, bivariate, and multivariate analysis focused on our adverse outcomes of acute renal failure and progressive renal insufficiency among all surgical specialties, and in general surgery specifically. Our results showed that ASA classification, preoperative mechanical ventilation, wound classification, ascites, sepsis, CHF, male gender, hypertension, preoperative metastatic cancer, dyspnea, diabetes, smoking, COPD, open management of the wounds, non-elective, and emergent operation were the risk factors for post procedural AKI across surgical specialties, as we as in general specifically. These findings will help the surgeons to evaluate the risk of post procedural AKI development and possibly take preventive measures.



Acute Kidney Injury, Surgery