DSpace at UTMB: Recent submissions
Now showing items 21-40 of 11029
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FACETS OF SOCIOECONOMIC POSITION AND THE ONSET AND PROGRESSION OF FUNCTIONAL LIMITATION IN MEXICO
The association between lower socioeconomic position and poor health has been observed across countries and health outcomes. Socioeconomic position is often measured by education, income, wealth, and occupation which are ... -
Validating Targeted Behavioral Markers for Teamwork Skill and Performance Outcomes in Simulation
The National Academy of Medicine, formerly the Institute of Medicine, asserts healthcare providers must demonstrate competency in teamwork (IOM, 2001). TeamSTEPPs® is a comprehensive instructional framework developed by ... -
ANIMAL MODELS FOR BEHAVIORAL CHANGES OR HEARING LOSS UPON ACUTE VIRUS INFECTIONS
Sequelae are defined as a condition resultant of disease, typically a chronic complication of an acute illness. Neurological sequelae are those complications involving the brain and central nervous system and can include ... -
Discovery and characterization of a newly emerged DENV serotype.
Dengue virus (DENV) is a mosquito-transmitted flavivirus that presents a substantial threat to public health worldwide. One third of the global population is at risk of infection and over 400 million cases of dengue are ... -
Pathology and mechanisms of increased M.tb growth and dissemination during co-infection with HIV-1
Around one third of the world’s population is latently infected with Mycobacterium tuberculosis (M.tb). M.tb and HIV have a deadly synergy that occurs during co-infection. Individuals with HIV infection are at significantly ... -
Examination of discharge settings and readmission rates following hospitalization for total knee arthroplasty
Total knee arthroplasty (TKA) is one of the most common surgical procedures performed in the United States with tremendous growth expected. Reducing unplanned hospital readmissions has become a focal point in minimizing ... -
“We’re Still Going”: A Critical Ethnography of Independently-Living Elders’ Healthcare Utilization to Maintain or Regain Their Health and Autonomy.
Elders becoming eligible for Medicare are projected to reach 72.1 million by 2030 (U.S. Census Bureau, 2011). Their numbers will challenge the healthcare system (HCS) and Medicare’s ability to provide equitable, quality, ... -
Autophagy and Inflammation During Rickettsial Infection
Rickettsiae are obligately intracellular bacteria that replicate in the cytoplasm of host cells. In my dissertation, I have studied the induction of autophagy by rickettsiae as well as the role of autophagy in the ... -
CELLULAR ALTERATIONS OF ADULT HIPPOCAMPAL NEUROGENESIS IN THE FGF14−/− MOUSE MODEL
Over the past decade, growing evidence indicates that adult neurogenesis (the production of functionally mature neurons from progenitor cells in the adult mammalian brain) is linked to the etiology of many neurodegenerative ... -
DISRUPTION OF THE HIPPOCAMPAL GABAERGIC SYSTEM IN THE Fgf14 ̶ / ̶ MOUSE MODEL
In CNS, cognitive function is greatly dependent on the functional integrity of gamma-amino-butyric acid (GABA) interneurons. These inhibitory interneurons modulate synaptic plasticity and intrinsic excitability of principal ... -
Role of TLS Polymerases in Replication of DNA Lesions in Human Cells
Cells are constantly exposed to numerous genotoxic lesions that inhibit replication. The inability of cells to correctly repair these lesions results in mutations or chromosomal aberrations that threaten the integrity of ... -
Exploring the Relationship Between Psychological Resources and Breast Cancer Survivorship using Path Analysis
Deborah K. Arnold PhD The University of Texas Medical Branch, 2016 Supervisor: Dr. Alice Hill Psychological resources (intrapersonal, interpersonal and informational) have the ability to influence cancer survivorship. ... -
A descriptive epidemiological review of hospital admissions for UTI from long term care facilities and a systematic review of strategies to reduce the risk of catheter associated UTI in long term care facilities in order to reduce these admissions.
Urinary tract infection (UTI) is a significant source of morbidity and mortality in the elderly. Urinary catheter use greatly increases the risk of contracting a UTI. Use of a urinary catheter has been shown to increase ... -
TRENDS IN LIFE EXPECTANCY AND MORTALITY: A COMPARISON OF HISPANICS AND NON-HISPANICS IN THE SOUTHWEST UNITED STATES, 1990 TO 2010
This project uses data from the National Vital Statistic System to study trends in rates and causes of deaths among Hispanics compared to non-Hispanics in the Southwest United States. Denominators are from the Modified ... -
EPAC1 AS A THERAPEUTIC TARGET FOR PANCREATIC DUCTAL ADENOCARCINOMA
The recent discovery of a new family of cAMP sensor proteins, exchange protein activated by cAMP (EPAC), ushered in a new era in cAMP signaling. EPAC is composed of two main isoforms, EPAC1 and EPAC2, whose roles in mediating ... -
Regulation of the FGF14:Nav Interactome by a GSK-3 Centered Pathway
Psychiatric disorders are complex, multifactorial diseases characterized by disruption of neural circuits, accompanied by an imbalance of excitatory and inhibitory inputs leading to dysregulations in neuronal excitability. ... -
A Review of Associations Between Traumatic Brain Injury & Addiction and Therapeutic Interventions for Addiction in the Brain Injured Population
The research linking drug and alcohol use with increased risk of sustaining a traumatic brain injury (TBI) has been well established. There is some evidence suggesting that the inverse relationship exists; that sustaining ... -
INDIVIDUAL DIFFERENCES IN IMPULSIVE ACTION AND TEMPORAL ESTIMATION: INTERACTION WITH THE SEROTONIN (5-HT) 5-HT2A RECEPTOR
The tendency towards patterns of impulsive behaviors and decisions extends across many neuropsychiatric conditions, such as substance use disorders, and leads to problematic consequences which may complicate effective ... -
Induction of Long-Term Immune Responses to Protect Mice against Pneumonic Plague: Development and Testing of Novel Live-Attenuated Mutants of Yersinia pestis CO92
Currently, there is no FDA-approved vaccine against the causative agent of the pneumonic plague, Yersinia pestis. Since both humoral and cell-mediated immunity are essential in providing protection against the plague, we ... -
Evaluating Seeding Galveston: Assessing Food Security and Health-Related Outcomes
Program evaluation is a crucial step in the success of community-based programs, as it allows stakeholders and community organizations to determine the success of our efforts and make changes where necessary to improve our ...