Mutations in polycystin-1 (PC1) can cause Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is a leading cause of renal failure. The available evidence suggests that PC1 acts as a mechanosensor, receiving signals ...

Cause of death (COD) determination by physicians on the death certificate can be difficult when the conditions leading to death are unclear or uncertain. The Center for Disease Control (CDC) recommends the classification ...