Mutations in polycystin-1 (PC1) can cause Autosomal Dominant Polycystic Kidney Disease (ADPKD), which is a leading cause of renal failure. The available evidence suggests that PC1 acts as a mechanosensor, receiving signals ...

Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of bubonic and pneumonic plague. Y. pestis is also a category A select agent based on its potential use as a biological weapon. Currently, ...

Existence of a strong relationship between protein's dynamics and its functional kinetics was suggested decades ago. Even though different groups investigated this relationship, technical difficulties and lack of appropriate ...

Continuous monitoring of cerebral blood oxygenation is critically important for successful treatment of patients with severe traumatic brain injury and patients undergoing cardiac surgery. At present, the techniques for ...

Proof of a presentation by Pasteur to the Commission Imperiale de Sériciculture in January 1867.

Proper hepatocyte function is vital for survival; hence unrepaired destruction of the parenchymal tissue leading to liver decompensation is devastating. Therefore, understanding the homeostatic process regulating liver ...

Figure demonstrating a method of determining mass during the weightlessness period of orbital spaceflight.

Photograph of Dr. Thornton conducting research during the STS-8 mission. This photograph shows Dr. Thornton holding an otoscope.

Neonatal hypoxia/ischemia (HI) is the most common cause of developmental neurological, cognitive and behavioral deficits in children. Although cerebral edema is a common outcome after HI, the mechanisms leading to the ...